Cystathionine β-lyase

Supplied as a freeze-dried powder form; 

Featured high specific activity and stability, as well as improved long-term and in-use stability; 

Simplify the process of reagent preparation by the accurate activity of CBL, reduced the difference  batch to batch.

Cystathionine β-lyase was found in plants and microbes is a pyridoxal-5′-phosphate (PLP)-dependent homotetrameric enzyme of approximately 35–40 kDa and catalyses the penultimate step of methionine biosynthesis, that is, α, β-elimination reaction, where cystathionine is hydrolysed into pyruvate, ammonia, and homocysteine. Subsequently, homocysteine gets methylated to methionine. The overexpression of CBL encoding metC gene in D-alanine gene knockout models of several bacteria was found to be significant for their sustenance in host cell environment. In addition, CBL also dictated the virulence of Salmonella enterica thus playing a decisive role in its pathogenicity.